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Melpo Christofidou-Solomidou Selected Research

Lignans

10/2021Late Inflammation Induced by Asbestiform Fibers in Mice Is Ameliorated by a Small Molecule Synthetic Lignan.
1/2020Ozone-induced enhancement of airway hyperreactivity in rhesus macaques: Effects of antioxidant treatment.
1/2018Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation.
5/2017Enterolactone Induces G1-phase Cell Cycle Arrest in Nonsmall Cell Lung Cancer Cells by Downregulating Cyclins and Cyclin-dependent Kinases.
1/2017Enterolactone alters FAK-Src signaling and suppresses migration and invasion of lung cancer cell lines.
2/2016Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice.
5/2015Flaxseed modulates inflammatory and oxidative stress biomarkers in cystic fibrosis: a pilot study.
12/2012Radioprotective role in lung of the flaxseed lignan complex enriched in the phenolic secoisolariciresinol diglucoside (SDG).
2/2008Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury.
6/2006Dietary flaxseed supplementation ameliorates inflammation and oxidative tissue damage in experimental models of acute lung injury in mice.

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Melpo Christofidou-Solomidou Research Topics

Disease

24Inflammation (Inflammations)
10/2021 - 05/2003
19Neoplasms (Cancer)
03/2018 - 08/2002
18Lung Injury
11/2017 - 01/2002
8Hyperoxia
06/2016 - 01/2002
7Pneumonia (Pneumonitis)
09/2019 - 08/2004
7Fibrosis (Cirrhosis)
04/2016 - 11/2006
7Ischemia
01/2016 - 08/2003
7Acute Lung Injury
05/2010 - 03/2002
6Lung Neoplasms (Lung Cancer)
05/2017 - 05/2010
5Pulmonary Fibrosis (Fibrosing Alveolitis)
04/2016 - 11/2006
5Reperfusion Injury
01/2013 - 04/2003
4Mesothelioma
10/2021 - 01/2015
4Malignant Mesothelioma
07/2016 - 01/2016
3Asbestosis
10/2021 - 07/2016
3Lung Diseases (Lung Disease)
10/2021 - 08/2004
3Edema (Dropsy)
05/2010 - 08/2009
3Thrombosis (Thrombus)
08/2009 - 03/2002
3Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
10/2006 - 08/2003
2Autoimmune Diseases (Autoimmune Disease)
10/2021 - 01/2019
2Neuroinflammatory Diseases
11/2020 - 01/2018
2Weight Loss (Weight Reduction)
09/2019 - 06/2011
2Sepsis (Septicemia)
01/2019 - 01/2006
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2017 - 08/2013
2Polycythemia (Erythrocytosis)
06/2013 - 03/2010
1Radiation Pneumonitis
10/2021
1Esophagitis
10/2021
1Pain (Aches)
11/2020
1Radiculopathy (Radiculopathy, Cervical)
11/2020
1Wounds and Injuries (Trauma)
11/2020
1Asthma (Bronchial Asthma)
01/2020
1Eosinophilia
01/2020
1Body Weight (Weight, Body)
01/2019
1Hypothermia
01/2019
1Cardiomyopathies (Cardiomyopathy)
01/2019
1Peritonitis
01/2019
1Pleural Diseases
01/2019
1Primary Graft Dysfunction
01/2019
1Heart Diseases (Heart Disease)
01/2018
1Atherosclerosis
01/2018
1Infections
01/2018

Drug/Important Bio-Agent (IBA)

15AntioxidantsIBA
11/2020 - 04/2003
12Proteins (Proteins, Gene)FDA Link
05/2017 - 08/2004
10LignansIBA
10/2021 - 06/2006
9AsbestosIBA
10/2021 - 01/2015
8LGM2605IBA
10/2021 - 03/2016
8secoisolariciresinol diglucosideIBA
11/2020 - 12/2012
7Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 08/2003
6CytokinesIBA
01/2018 - 06/2011
4EnzymesIBA
01/2018 - 03/2002
4Biomarkers (Surrogate Marker)IBA
11/2017 - 11/2006
4Hydroxyproline (4 Hydroxyproline)IBA
01/2014 - 11/2006
4Oxygen (Dioxygen)IBA
06/2013 - 06/2006
4Platelet Endothelial Cell Adhesion Molecule-1IBA
11/2006 - 03/2002
3Messenger RNA (mRNA)IBA
01/2020 - 01/2017
3LipopolysaccharidesIBA
09/2019 - 06/2006
3EndotoxinsIBA
01/2018 - 08/2009
32,3-bis(3'-hydroxybenzyl)butyrolactone (enterolactone)IBA
05/2017 - 06/2006
3Superoxides (Superoxide)IBA
01/2016 - 11/2009
3Oxidants (Oxidizing Agents)IBA
11/2011 - 03/2002
3Glucose OxidaseIBA
11/2009 - 03/2002
3CatalaseIBA
11/2009 - 04/2003
3ThrombomodulinIBA
08/2009 - 03/2002
2Amphibole AsbestosIBA
10/2021 - 01/2019
2Peroxidase (Myeloperoxidase)IBA
08/2021 - 01/2018
2LipidsIBA
05/2021 - 10/2006
2Superoxide DismutaseIBA
01/2018 - 11/2006
2KL4 surfactantIBA
11/2017 - 10/2006
2InflammasomesIBA
01/2017 - 01/2016
2Malondialdehyde (Propanedial)IBA
01/2014 - 01/2009
2Radioisotopes (Radionuclides)IBA
04/2013 - 06/2011
2FibrinIBA
05/2010 - 08/2009
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 08/2004
2AntigensIBA
04/2007 - 03/2002
2Pharmaceutical PreparationsIBA
04/2007 - 05/2003
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
11/2006 - 05/2003
2AcidsIBA
06/2006 - 08/2004
13-nitrotyrosineIBA
11/2020
1OzoneIBA
01/2020
1Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
01/2020
1Interleukin-6 (Interleukin 6)IBA
01/2020
1salicylhydroxamic acid (SHAM)IBA
09/2019
1Anti-Bacterial Agents (Antibiotics)IBA
01/2019
1Ertapenem (Invanz)FDA Link
01/2019
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
01/2018
1Protective AgentsIBA
01/2018
1Hypochlorous Acid (Hypochlorite)IBA
01/2018
1RNA (Ribonucleic Acid)IBA
01/2018
1Interleukin-27 (Interleukin 27)IBA
01/2018
1O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA
01/2018

Therapy/Procedure

6Radiotherapy
10/2021 - 05/2010
4Therapeutics
05/2017 - 08/2003
3Chemoprevention
01/2018 - 02/2016
2Lung Transplantation
04/2016 - 01/2006
2Drug Therapy (Chemotherapy)
02/2014 - 08/2013
2Intravenous Injections
08/2003 - 02/2002
1Craniotomy
09/2019
1Length of Stay
01/2019
1Ligation
01/2019
1Punctures
01/2019
1Artificial Respiration (Mechanical Ventilation)
01/2019